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Menopause in women or low testosterone levels in men, Poor nutrition such as low-intake of calcium and vitamin D, Crohns disease, celiac disease, and other inflammatory bowel conditions that affect your body in absorbing nutrients, Calcium supplements, magnesium, iron, and zinc multivitamins, Cancer medicines such as bevacizumab or thalidomide and if youre undergoing chemotherapy. Newsletter archive, Data Based Medicine Global Ltd. Alendronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. She has had none of the horrible side effects mentioned in these posts so it must work for some people. She has stopped the tablets. Small movements and small gentle breaths allow me to feel ok and for my muscles to be still. I have v v mild connective tissue disorder (not rare) also. Already taking Adcal D3 and steroids. The method comprises the steps of reacting a compound of formula I with H 3 PO 3 wherein R is an imido group and R 1 is selected from the group consisting of chloro, bromo, iodo, fluoro, hydroxy, amino, OR 2 or OC(O)R 2 , wherein R 2 is C 1 -C 12 alkyl, C 1 -C 12 cycloalkyl or C 1 -C 12 aryl; and then reacting the . And dairy products reach in calcio. The side effects are horrific. Following breast cancer they want me to take Aromatase Inhibitor along with a Biphosphonate Clondronate or Zolendronic so my question to everyone out there will these other biphosphonates result in similar pain? Hi, I am 47 years old and recently found out I have osteopenia every where and osteoprosis in on of my hips. The first indication I had that something was amiss was in September 2009 I took three anti-sickness pills and had some very strange reactions. Itching in my left shoulder/arm, have gained weight and my mood has changed. I feel much better and fitter than before. Typically, doctors recommend taking osteoporosis medication for 3-5 years. I am 81 years of age. She sent me to a specialist for a second opinion and he said take it. The side effects are bone pain, joint pain and bruising, numbness in the face and lips. Hi Everyone Abstract. Hey Ive been diagnosed with polymialgia rheumatica too i was prescribed predisolone vit d evacol and now AA Im not having any side effects from it yet but reading all of these comments Im worrying about wether I should take the alendronic acid Ive only taken two up to now but have had no problem with it yet It scares you a bit, Hi I have just been precribed alendronic acid I have not taken it yet as I have had a bad cold. They began to itch the next day, ( I took my 5th dose of medication) and they were slightly better but I called my doctor and got in To the office Friday. There are over 200 million people worldwide who have osteoporosis. Some medications may interact with alendronic acid and may cause it not to work effectively. I still do not feel right and have added pain, although a bit better than it was. , I started taking foxomax at the age of 38 and took it weekly for many years during this time the foxomax I was taking became alendronic acid I had no idea the dental problems it could cause till I need a tooth out I I had to come of alendronic acid and wait a period of time before having my tooth out but to my shock before I went back on alendronic acid it was suggested I have a dexa scan I didn,t think there would be any thing a miss how mistaken I was although I had been on the alendronic acid for years it hadn,t worked for me and my bones where thinner than they should be I now have ostiopenia and take ad cal, I am dealing with broken teeth and mouth issues due to foxamax. Rare and serious effects such as femur fractures and jaw problems (osteonecrosis of the jaw) have been reported. Looking back over the past four years of this journey, I realised that whenever I took any other tablets my symptoms worsened dramatically. Terms|Privacy, Research Forum for Enduring Sexual Dysfunction, https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA, https://www.druglawsuitsource.com/canada-fosamax-lawsuits-settled/. hi i broke my wrist last year and because of this I had a bone scan I was told I had osteoporosos in the Spine and hip im 57 and lead a active life ive on vitamin D daily and AA 70 ml weekly I took my one this morning a number of hours after taking this table I have had very bad stomach cramps and I have not left the bathroom and my head is bad. All Rights Reserved. Small blisters on various areas of my body. muscles ache, no energy, depression. I began to take as prescribed and do not have any problems until 6 days after my 4 th dose, I was awakened in the night with uncomfortable, aching wrists. the shaking could be from one of the new meds, but it started slightly in the summer. If you have osteoporosis, bone fractures commonly occur in your: Below are the most common factors that may put you at risk of developing osteoporosis: Youre also at a much higher risk of developing osteoporosis if you have health conditions like: Osteoporosis wont give you any symptoms, but you should visit your doctor if youre in doubt, especially if youre approaching menopausal age. I am 62, healthy and active. Since taking it I have a painful jaw,dry mouth and severe constipation, bloated stomach and a general,feeling of being unwell I spoke to my GP a few weeks ago about my painful jaw and he told me this was quite common and to carry on taking it but. Needless to say I will never take another one and I would like to know whether anyone knows how long Alendronic Acid takes to leave the system. Alendronate is also used to treat Paget's disease of bone. Im considering ringing the hospital myself to see if I can have one done. I think its great that we can come in here and discuss how we are feeling. I chose the infusions and, after two infusions, the Pagets was seen to be in remission. I was prescribed alendronic acid as my DEXA scan showed mildish osteoporosis when I started arimidex. This is just too weird. Anyway, I started to take them three weeks ago and I seem to have been fortunate in that I have had very few side effects but, after reading all these reviews, Im not sure I will carry on as Im fit and healthy with no pain. Below are the most common things you can do to care for your bones after you stop taking alendronic acid: You probably want to get rid of taking alendronic acid as soon as possible and do the natural way of treatment to avoid serious side effects in the future. It can support your bones depending on how long you have taken medicine. Please check with your doctor before stopping taking alendronic acid and switching to alternative treatments. Have other peoples side effects, particularly bone and muscle pain gone away after discontinuing this drug. Side effects developed gradually. This is me! Really concerned as Ive never ever had bowel problems!!!! re the first strange vivid dreams has been my nearest experience. I have had to keep off coffee, fruit and anything acidic for months, I even tried gaviscon which made me feel sick and had a bloated stomach for 2 hours. jaw ? Alendronate (alendronic acid) Alendronate is an osteoporosis medication. Nothing too spectacular to report. I had had a two year bone scan and been told that my bone density had increased, so as far as I was concerned, the drug was working and all was well in that particular area. I took Alendronic Acid for 6 months and stopped 5 months ago. I am also diabetic 2 (no drugs diet only) coeliac (wheat and gluten free. I have been told I will have one in 2 years. By this time my body was still, so I went home feeling scared and utterly distraught. Ive just discovered that lack of it can be at the root of fatigue, depression, low body temperature, and many other issues. We engineered nanomedicine with the stealth corona made up of densely packed bone seeking ligand, alendronic acid. Everything was find. check your brand of alendronic acid may contain gluten, Dear Jane If I apply pressure to my temples, my headache lessens. In rare cases, alendronic acid may cause a serious allergic reaction ( anaphylaxis ). My GP told me to take alendronic acid with the calcium and vit D tabs 5 or so years ago (in my mid 40s), after a DEXA scan showed I had mild osteoporosis already. Federal drug regulators and researchers say that Fosamax, a drug thats supposed to help with bone growth, is linked to this rare dental disease thats also called Dead Jaw Syndrome. Its bad enough living with PBC and all that entails for the rest of my life, but to go through what all of you good people have gone through NO WAY DANNO! It could give you terrible side effects. If you missed a dose, take it the following day and do not double take it to avoid overdosing. In fact we were three quarters of the way through our time together before I happened to mention I took alendronic acid. pope francis indigenous peoples. I decided to stop. Muscle pain all the time hot sweats but put that down to menapause each time going to doctors about my symptoms only to be told the good will out way the bad Iike hell did it only at the end of july I was walking minding my own business with friends in torquay on holiday 1 day into my holiday I was crossing the road &my leg broke in front of me so I sustained a femur fracture due to AA which has been confirmed twice it was the AA that has caused this I have now come off them my sweats have stopped along with the others symptoms all stopped all off most I put down to a long menapause. Feel quite worried reading all these comments but thoughts Id just let people know that my 90 year old mother has been taking AA plus Adcal for about 8 years after two falls in which her wrists were broken ( falls due to hypotension caused by drug she was currently taking. I have now been off Alendronic acid for two weeks or so, and at the moment im not noticing very much improvement. Ive taken a covid test because these days thats what you do if you feel ill at all. . Had another car ride, but then it flared up again, sometimes I limped all morning. alendronic acid has destroyed my life I am not in your age group Jane bit I can appreciate Yor feeling left out. A. alendronic acid has destroyed my lifealendronic acid has destroyed my life ego service center near me Back to Blog. Its such a dilemma. oscar the grouch eyebrows. june 2022. Until this doctor expressed his surprise that I was taking it, and his opinion that it was possibly the cause of my problems, no one had ever raised any questions about it. Cholesterol-lowering medications -- A class of medications known as bile acid sequestrants (including cholestyramine, colestipol, and colesevelam), used to treat high cholesterol, may interfere with normal calcium absorption and increase the loss of calcium in the urine. Im 54 years old and after having a Dexa scan, was told that I have Osteoporosis. You must take your dose on the same day each week. For oral liquid medicine, use the dosing syringe to measure one unit (70 mg in 100 ml) of oral solution and take it once a week. Took 1 pill of AA. I take Alendronic tablets as I had breast cancer and take the tablets for continuing bone health. So, what happens now, does my Osteoporosis get progressively worse over time? There has to be a better way. However, it usually takes 6-12 months of ongoing medication to get its full benefit. Whenever Ive mentioned it to my GP, its sort of brushed away. I will never take drugs like yours again. I have an annual blood test at hospital for gluten. Not feel normal anymore, weak dizzy loosing balance and sight too which could also be caused by oprazole to protect stomach. Sister told the doc she intends taking Boron. I wanted to mention to you that Ive just watched a video by Dr Jorge Flechas, called Reverse Osteoporosis with Boron. I was told I had osteoporosis in 2004 and was put on Fosamax for about 6 months after which I was switched to Actonel. Hi. Like just for a moment I couldnt remember where I kept my masking tape. Mayo Clinic Press. Fast forward to 2008. A blood test followed and the inflammation was evident in the test, but I did not test positive for RA which I was worried about. You uesly get shake from over active thyroid, I know because that what I have, I have been put on alendronic, I havent taken them yet, its very frigthening, not sure what to do, Im 63 and have gone to the gym most ofy life, I dont want to there guinea pig,. This settled after a few days The side effects of this drug are well documented and you can see them at :- Am I the only one the suffer from these bad side effects after taking it for the first time. There are 8,218 reported reactions, bear in mind many dont report the side effects to the Yellow Card Scheme. Its essential to take your dose while your body is upright. My mother is 83 and has been on this drug for over twenty years with only one bone scan. It begins as minor dental problems and can escalate to permanent jaw damage. She doesnt have osteoporosis but they just put her on these. I will not be taking another one! I read its the same Acid in cleaning products! Maybe tomorrow I will get better direction from the physician. That was the last tablet I took of that drug. So I have decided that it must be the alendronic acid and I have stopped taking them its making my life unbearable. Wait for at least 30 minutes after taking the drug. Alendronic acid contains an active ingredient, alendronate sodium, a bisphosphonate. Im going to stop taking Alendronic acid. I would be grateful for any help or advice I have had OA in my lumber Thorasic and Cervical regions of my spine and also in both of my hips and was given a Bone density scan which showed the OA has progressed to Osteopena for this the consultant prescribed Alendronic Acid tablets 70mg which I take once a week from 30/03 /13 . Editorial Note: We want any accounts of adverse or interesting events on drugs or new uses for drugs from people on them or doctors, pharmacists or others trying to manage the effects of drugs. She was a keen walker and is feeling very worried. I wont be taking it as I feel I may be able to find a natural alternative. My face had also experienced this and I have had swollen lips. This drug is also used to treat Paget's disease. Overdosing may lead to an upset stomach, heartburn, and ulcers. I have been put on prednisone and even though my bones are ok I have been prescribed AA as prednisone destroys bones. I hope you are ok. I was wondering if the side effects of the drug actually go away, and if they do, how soon can I expect to see some sort of improvement? From day one I didnt believe that my body needed them but was told that When your taking steroids the additional meds are also needed & I was told this by more than one GP!!! I have been taking them for about 5 weeks. The pain has travelled to her shins since stopping it. Who else out there has a similar story? Bizarre feelings in my head, my arms feeling like they didnt belong to me, I felt faint and dizzy, my heart was pounding and had moments when it seemed out of rhythm. May 2013, 15:46. Taking alendronic acid can help if you have, or are at risk of developing, osteoporosis. Just had to reply to your post! This prompted me to do more research into alendronic acid, but instead of looking up this generic term, I tried the brand name Fosamax. I Have been taking Alendronic Acid Tablets for 11 months now. 2023 The Heart & Brain. So I still have not gotten ANY doctor to tell me that the osteo drugs were what CAUSED this but I dont see any other possible cause. My lower face is completely swollen on the left side. Ive only taken one tablet going to speak to Dr tomorrow. I had been suffering with a terrible burning tongue for eight months and I also had aching legs, this burning tongue I put down to the gallstones I have got. How Alendronic Acid works Alendronic Acid is a bisphosphonate. Today is Wednesday! judy. This helps to improve bone strength and makes the bone less fragile. Shingles 6 months ago and Dr. says this is result of shingles. prevent cancer spreading to the bone. I am otherwise healthy and have never taken any meds in my life. I also ate one energice bar. If it is common for headaches, dizzy spells and blackout reportsshouldnt this concern those that live alone, for both GP and patient? I am 70 and keep fit by walking everywhere. Want to take back controle before I find myself surrendering myself to more drugs. When I initially had a bone scan they said Id have another one after three years, Ive never had another one. No other cause but the medicine . Now, the only exercise I get is pottering around my house or gently along my local high street. Just dont know what to do for best. I had a complete hysterectomy 24 years ago but could not tolerate HRT therefore was susceptible to osteoporosis but I had slipped through the net according to my doctor and only got a dexa scan in August 2017. I will not take the poison again. Im 62. So I duly took the AA70, now on third month. For more about osteoporosis and medication, see Fragile Doctors: Iatroporosis. Inhibiting osteoclast function, as bisphosphonates do, lessens bone resorption. Stop taking your next dose if you experience rash or hives, swelling of your face, lips, or tongue, and trouble breathing. Hi Ive had AA and it made me feel terrible! Hi When I showed this to my GP, he said that is not correct and the book was wrong. It slows down your body from producing cells that break down your old bones, giving enough time for bone-building cells to spur the growth of new bones. I wish everybody all the very best and thank you for your feedback. It has given me bad acid reflux. Also does anyone know what element of AA gives you the aches and pains so that I know if it will be safer for me to take the Risedronate please? In 2002 I discovered via the internet that I wasnt desperately ill with an anxiety disorder that only Seroxat could fix. I also have had a bone scan pre drugs so it would be interesting to find out when I can have another scan to see whether there is an improvement or at least no further loss apart from normal degeneration of bone. The Royal Osteoporosis Society website is very detailed and useful, with info on exercise you should do more of it which must be weight bearing more so than just walking and promote balance. Because of how I tend to react and my blood test results, I thought I would research the new meds first and Im now very pleased that I did. https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA Did your painn go away after it left your system. This vitamin helps your bones absorb more calcium. Can you keep us posted on whether it goes down again, and if it does whether you or anyone can work out what it is about the drug is causing this to happen and what your doctor suggests when you get to talk to him. The last two weeks I have felt terribly sick, not eaten much had terrible bloated stomach, one Sunday I felt so ill I had to do a 111 saw a medical person and was given a thorough test being told everthing was ok, I had put it all down to my gallbladder which it wasnt. She was put on Alendronic acid as she had a fall broke her wrist and has had breast cancer. I dont know if this is due to alendronic acid or the letrozole I am taking for breast cancer. Reading these reports,i am now worried.am 63 & After taking AA 70mg per wkfor 2months,& all the awful side effects mentioned here,consultant wants to try zoledronate yearly infusion. The doctor put me on ADCAL D3 and alendronic. Took one tablet within 24hrs experienced labour pains & felt like Id been kicked by a horse in the back continued for 4 days, gradually wore off and I refused to take another Alendronic pill again. Land degradation also has serious knock-on effects for humans, such as malnutrition, disease, forced migration, cultural damage, and even war. My doctor didn't mention the gastrointestinal issues when prescribing Alendronic acid and neither did she mention alternative ways of improving my situation. Cut out all rubbish from your diet, anything processed or ultra-processed, with tiny treats to stop it being too depressing! So I left the surgery with a prescription for alendronic acid and a promise I would have a scan after two years, not the usual three. I had open heart surgery at the end of December and didnt take the alendronate for a couple of weeks and coincidentally the swelling went I thought maybe it was caused by fluid build up due to my heart condition and thats why it was better. take personal responsibility for themselves. This caused the bone to shatter like glass ! Then, you can resume eating and drinking normally. Stopped AA & CAL3D immediately!! Make sure the spinach is cooked to get rid of the oxylates which inhibit calcium absorbtion; so cook your spinach. But after a yr i got a very bad back, ended up a right angle for 6 wks, now i have just pushed hard with a screwdriver and got such a pain in my side. If youve taken alendronic acid for 2 years, your bones might still benefit from it for up to 5 years. Many thanks for all your comments re Alendronic Acid, these have been most helpful in my decision to take this drug. If recommended to be taken twice a day, you should have it during lunchtime and dinnertime. I tried the Alendronic acid one a week tablet last night and was so unwell that I nearly called an ambulance, my symptoms were very cold ie chattering teeth, pains all over body, sore head,jerking arms and very unsteady on feet, and nausea. It might surprise some readers to learn that bone is. She had breast cancer over 5 years ago and had a fall recently and broke her wrist. Ive only had one tablet of the Alendronic Acid yesterday, but seem to have quite a few of the side effects so wont have another again, and am miffed to see that people have problems for weeks even after one tablet. I got a book on osteoporosis from the library and it explained against taking alendronic acid and any other medication that contain biphosphates. Next morning extreme pain in my back and kidney area. One thing concerns me! Alendronic Acid prevents the loss of bone that occurs in women after they have been through the menopause and helps to rebuild bone. This is a dangerous drug. Hello I am 66 and like many of you am hating taking this drug, I had breast cancer 4 years ago,so am still taking Anastrosil as it was Hormone related,which in turn apparantly helped causing bone density loss, so ws then diagnosed with osteopenia Your doctor will put into consideration the lifestyle changes youve made. After reading the comments I will not be taking it again. Due to Covid I only had a telephone consult with an Endocrinologist. Take the medicine on an empty stomach. In addition, previous side effects were swellings and wealds all over, itching and bloatedness. Thanks so much & best of luckKatie (New York), I had a fall downstairs nearly 2 years ago and broke my back, Ive been on adcal 3 for years do my doctor put me on alendronic acid, since then my health has been awful, Im 66, it takes me to get out of bed in the morning I can hardly walk at times,my teeth are crumbling asked dentist was it because of the tablets he said no but Im sure it is,Ive up get a root extraction on Thursday as my tooth crumbled and left the root of the tooth,he said he is concerned about me being on the alendronic acid and if he cant get the root out I will be sent to hospital,thats me finished with these tablets they have ruined my life. My opinion is , go and see your GP for advise ! I was diagnosed with osteoporosis two weeks ago, so I just took one Sunday. My body jerked violently and out of control for hours. The effects of alendronic acid may occur after 1 month of taking it. Ohh my Goodness thank you so much for your post. As far as the AA, its track record shows there have been dental issues in some people. Yes and i stopped taking them my stomach was so bad i could only chest breathe. Hi Rowena. Does anyone know if theres a link between the 2 drugs or if theres a suitable alternative? I am interested about the post that said you should only really take for 2 years does anyone else have info on this. But, due to some factors, your bone mass could decrease rapidly, and your body could break down bones much faster than replacing them. I feel so Ill, but after reading the comments regarding AA, Im not sure, if its the AA causing these problems, Im afraid to take my next one, on Thursday. Like a lot of people I was researching AA70 when I came across this group. Tablets the gift that keeps giving, I have just had a DXA scan (following a wrist fracture) and it came back I have really bad osteoporosis. Its essential to take calcium supplements and vitamin D3 at least 2-4 hours before your first dose of alendronic acid. She is currently in a lot of pain when she walks. Are we not sentient beingsthey are not the be all and end all. 74, fractured hip. It can worsen the side effects of alendronic acid in your stomach and prevent the drug from working. You should eat more foods that promote healthy bones. There is a Group related to these awful side effects on Facebook called Reglan Support Group (Primperan/Metoclopramide Read the devastating effects this drug has had on people taking it. Armed with more natural solutions which I have been taking anyway but paying more attention now. My body awareness tells me otherwise. This drug is only available for prescription and should be taken with caution. My Seroxat story is classic and a repeat of so many other peoples. Alendronate works by slowing down the cells that break . I ran on a treadmill for twenty minutes and I could push my weight in kilos on the leg press. My advice is dont risk your health when the adverse effects are so clearly documented. Glad Im not alone with these problems,thought i was going mad, hi I had zolondronic infusion no problem ,tablets i cant tolerate so I have hit and missed with them ,I told my consultant and the nurses at the hospital but went unanswered said they would sort it ,five weeks a go I fractured my spine so now Im waiting to see what they going to do Ive been honest with them said i skipped a lot cos I felt sick all the time ,Ive opted for infusion,told them that I did tell them ,but now because Ive fractured my spine Im worried that my bone is bad ,bone density scan and hopefully they will sort infusion out for me .I dont like the tablets,I take vitamin d and c .Im trying to help myself just hope its not too late .wouldnt mind I fell off a ladder about two years ago straight onto my back legs and head fell backwards flat and not a broken bone and I had had a density scan just before the fall. What an awful position to be in! And yes side effects are happening, muscles ache, jaw aches, I did have an X-ray on my jaw and its fine TG. The hospital talking about infusions once a year but still waiting for a appointment. Where do you live Jane hope you dont mind me asking. I took my first Alendronic acid tablet last Sunday. We would be very interested in accounts of what happens when people take RxISK reports to doctors. Your body naturally breaks down old bones and replaces them with new bone tissues to support your skeletal system throughout life. Sunday night started feeling unwell, sleepless night, sweating and chills. I am worried about it as it seems to be getting worse. Thank you for all y9our input re: Alendronic Acid. I read the leaflet and decided to google. It hurts to walk on my feet. Your dosing may depend on your age, how severe your bone condition is, other medical conditions you have, and your reaction to the first dose. I attributed this to having a 12 hour car ride and driving 6 out of 12 hours. It may put you at risk of jaw bone damage. But its come to my attention that long term , Yes my muscles ache and my arthritis in joints have worsened constant tummy upsets I put down to too much gluten! Were proud to be a team of writers who are truly passionate about all things health.Coming together from all parts of the world, we share a common goal of helping serve many with our comprehensive research and clear writing style. 6.5 Nature and contents of . Methods: This was a randomised, double-masked, double-dummy multicentre international study (75 centres in 27 countries in .